DOI: 10.29245/2578-3009/2019/1.1181 View / Download Pdf
Antonia I. Athanasiou*, Adamantios Athanasiou, Steven D. Spandorfer
Ronald O. Perelman and Claudia Cohen Centre for Reproductive Medicine, Weill Cornell Medicine, New York, USA
Commentary: An Allele-Specific Functional SNP Associated with Two Systemic Autoimmune Diseases Modulates IRF5 Expression by Long-Range Chromatin Loop Formation
DOI: 10.29245/2578-3009/2020/1.1182 View / Download Pdf
Hlaing Nwe Thynn, Xiao-Feng Chen, Shan-Shan Dong, Yan Guo, Tie-Lin Yang*
Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics & Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, P. R. China
Rowland Utulu1*, Joseph Urang3, Aishat Usman1,2, Neni Aworabhi1, Ugochukwu Osigwe2, Muhammad Shakir Balogun1,2, Eniola A. Bamgboye4
1Nigeria Field Epidemiology and Laboratory Training Program
2African Field Epidemiology Network (AFENET), Abuja
3Rivers State Primary Healthcare Management Board, Port-Harcourt, Rivers state, Nigeria
4Department of epidemiology and medical statistics, faculty of public health, University of Ibadan, Nigeria
Background: WHO African region set a target for elimination of measles by 2020 and recommended member states adopt a case-based surveillance system. WHO AFRO guidelines for measles surveillance state that an optimally performing surveillance system is crucial to elimination of measles. Rivers State is one of the high burden states for measles in southern Nigeria.
Objective: This study assessed the performance of the measles case-based surveillance in Rivers state, Nigeria.
Methods: We reviewed measles case-based surveillance data in Rivers state, Nigeria from year 2011-2018.
Results: A total of 1,731 suspected cases were reported with 1,128 (65.2%) confirmed cases of measles. Majority were confirmed by epidemiologic linkage 907 (80.4%) while laboratory confirmed cases constituted 206 (18.3%). Age group 1-4 years was the most affected 443 (42.6%). For cases with vaccination status available 425 (53.1%) were unvaccinated. No discarded cases were reported from 2016 to 2018. Non-measles febrile rash illness rate target of ≥2 per 100,000 was not achieved at any point in the eight-year period. The proportion of districts/LGAs reporting >2 Non Measles-Non Rubella Febrile Rash Illness cases/year was above the minimum target of 80% in just four years.
Conclusion: The surveillance system performed poorly with sensitivity and representativeness less than optimal. Measles elimination must leverage upon existing structures for polio elimination to improve surveillance. A more detailed analysis of the system is essential to identify all the gaps that may retard elimination efforts.DOI: 10.29245/2578-3009/2020/1.1183 View / Download Pdf